Per the Missouri Department of Health & Senior Services and recent updates, the following conditions qualify for medical marijuana certification:
Cancer
Epilepsy
Glaucoma
Intractable migraines unresponsive to other treatment
Chronic medical conditions causing severe, persistent pain or muscle spasms (e.g., multiple sclerosis, seizures, Parkinson’s disease, Tourette’s syndrome)
Debilitating psychiatric disorders, including PTSD (must be diagnosed by a state‑licensed psychiatrist)
HIV/AIDS
Terminal illness
Conditions normally treated with prescription medications that may cause dependence, if a physician believes cannabis is a safer alternative
Other chronic, debilitating, or medical conditions in the physician’s professional judgment, including but not limited to:
Hepatitis C
ALS (Lou Gehrig’s disease)
Inflammatory bowel disease (IBD)
Crohn’s disease
Huntington’s disease
Autism
Neuropathies
Sickle cell anemia
Alzheimer’s disease agitation
Cachexia (wasting syndrome)
Missouri’s law is intentionally broad: physicians have discretion to certify patients for other chronic or debilitating conditions not explicitly listed, if they believe medical marijuana could provide relief. This flexibility means many residents with serious health issues may qualify.